45 yr female with anasarca

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Case presentation:


45 yr old lady who is a housewife and

K/C/O DM 2 since 5yrs and HTN since 1yr,she  was apparently normal 6months back,used to develop pedal edema on and off  aggravates on walking and relieves on taking rest for which she was taken to nalgonda hospital and the doctor had advised her to decrease the fluid intake and gave some medications.It was associated with shortness of breath grade 3.

5days back she had developed pedal edema which got progressed and developed abdominal distension,facial puffiness associated with decreased urine output,sob even at rest  and chest pain on right side, non radiating with intermittent palpitations.

pedal edema was pitting type,not associated with fever, burning micturition,hematuria and frothy urine.She was taken to the same doctor and he had referred her to our hospital due to deranged RFT.


DAY1

She came to casualty with pedal edema, distended abdomen,facial puffiness and no urine output since 3days.

personal history-

diet is mixed, appetite-normal, sleep-adequate, bowel-constipation since 3days,anuria since 3days,habbit of tobacco chewing since 8yrs

O/E-

pt is conscious, coherent and cooperative

pallor is present,

no signs of icterus, cyanosis, clubbing,koilonychia and lymphadenopathy.

ulcer noticed on right sole. 


vitals-

 afebrile

 bp-180/80mmhg,

pr-84bpm

rr-13cpm

CVS-S1S2 heard,no murmurs

RS-BAE present,NVBS

P/A- distended,

CNS-

pt is conscious and well oriented to time,place and person

speech-normal

motor and sensory system-normal

cranial nerves - intact

cerebellar functions-normal





investigations ordered on DAY1


provisional diagnosis on admission-

acute kidney injury with metabolic acidosis with ? nephrotic nephritic syndrome with iron deficiency anemia

treatment given-

1.inj.NaHCO3 100 meq/iv/stat in 100 ml NS

2.syp.POTCHOLR  15 ml in one glass water tid

3.w/h all  OHA,anti hypertensives


DAY2

pain abdomen and no passage of urine

no suprapubic tenderness

no burning micturition

O/E-

pt is c/c/c 

afebrile

bp-130/80mmhg

pr-84bpm

rr-20cpm

CVS-S1S2 heard

RS-BAE present

P/A-distended,non tender

Investigations-



treatment-

1.inj.HAI  according to sliding scale

2.t.OROFER xt bd

3.t.PAN 40 mg od

4.inj.LASIX 40 mg iv bd if systolic bp >110mmhg


DAY3-

pt developed severe shortness of breath with metabolic acidosis and refractory anuria with bp-170/90mmhg,central line was placed and dialysis was done in the morning.

ophthalmology referral was taken and moderate hypertensive retinopathic changes were seen.

investigations after dialysis on DAY3-

hemogram-



Final diagnosis-

? NEPHROTIC SYNDROME WITH DIABETIC NEPHROPATHY WITH K/C/O DM AND HTN

treatment-

1.inj.lasix 40mg iv bd

2.tab.dytor 20mg of po

3.inj.HAI S/C according to sliding scale

4.tab.telma 40 mg od po->tab.nicardia 10 mg po/sos

Stopped telma

5.tab.orofer ct bd po

6.inj.erythropoietin s/c twice weekly

7.tab.nodosis 500 mg bd po

8.tab.shelcal ct po/op

9.syp.potcholr 15ml in one glass water tid

DAY 4-

C/o pain abdomen with facial puffiness, abdominal distension and pedal edema 

Pt is c/c/c well oriented to time,place and person

Pallor present

Weight-53kgs

Vitals-

Afebrile

Bp-150/90mmhg

Pr-90bpm

CVS-s1s2 heard

P/A-distended,tender

Dialysis with blood transfusion started from 9pm

Abg on day 4




Cxr on day4

DAY5
NO FRESH COMPLAINTS,PAIN ABDOMEN (RESOLVING)
PASSED STOOLS TODAY
I/O-750/100ML,WT-51KG
PALLOR+
NO FEVER SPIKES
BP-160/90MMHG
PR-90BPM
RR-25CPM
CVS-S1S2 HEARD, RS-BAE+
P/A-SOFT,NON TENDER,
CNS-NFND
Investigations ordered on day5-
1.Renal vein Doppler to rule out renal vein thrombosis-
Treatment added-
1.Syp.lactulose 30ml bd
2.protein x powder 2tbsp in one glass milk bd
3.inj.MONOCEF 1gm IV bd

DAY6-
NO FRESH COMPLAINTS
I/O-600ML/100ML
STOOLS PASSED
NO FEVER SPIKES
PALLOR+,WT-53KG
VITALS-
BP-150/80MMHG
PR-90BPM
GRBS-170MG/DL
CVS-S1S2+
RS-BAE+,CREPTS IN BOTH LUNGS
CNS-NFND
INVESTIGATIONS-
CBP-
abg-
rft-
cxr-



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